Should diuretics be first line for hypertension?

Should -blockers and diuretics remain as first line therapy for hypertension? Thiazide-Type Diuretics and -Adrenergic Blockers as First-Line Drug Treatments for Hypertension

Systemic arterial hypertension affects 72 million US adults and an additional hundreds of millions of persons worldwide.1,2 Most of these are candidates for pharmacological treatment to reduce risk of cardiovascular disease (CVD) events, based primarily on a very large body of epidemiological and intervention research in humans. Because of this high prevalence and the cardiovascular consequence...

Should atenolol still be recommended as first-line therapy for primary hypertension?

antihypertensive treatment should reduce the incidence of cardiovascular morbidity and mortality as well as total mortality. For four decades, beta-blockers have been widely used for the treatment of hypertension and are still proposed as first-line drugs in national and international guidelines. Numerous prospective, randomised studies have established beyond any doubt the efficacy of beta-blo...

Should ablation be the first line treatment for supraventricular arrhythmias?

Catheter ablation remains a good first line choice for the palliative treatment of symptomatic typical atrial flutter.

Should hypertension be treated with angiotensin-converting-enzyme inhibitors, calcium-channel blockers or diuretics?

Should atrial fibrillation ablation be considered first-line therapy for some patients? Why Atrial Fibrillation Ablation Should Be Considered First-Line Therapy for Some Patients

Atrial fibrillation (AF) is an increasingly common disease that affects patient morbidity and mortality. To date, treatments of AF have been frustrating, serving at best to palliate this arrhythmia. AF ablation, on the other hand, has emerged as a promising new treatment strategy. In contrast to rate control or antiarrhythmic drugs, ablation offers the possibility of a lasting cure. When ablati...